Sometimes misery is so great that good, righteous people give up hope

Job 7:3-6

So I am made to possess months of misery, wearisome nights are appointed to me. When I lie down, I say, ‘When will I arise, and the night be gone?’ I toss and turn until the dawning of the day. My flesh is clothed with worms and clods of dust. My skin closes up, and breaks out afresh. My days are swifter than a weaver’s shuttle, and are spent without hope.